US scientists have built a new tool that maps thousands of proteins across whole tissue — and it is already pointing to promising new targets in the hunt for Alzheimer’s treatments. The work, from University at Buffalo researchers, was reported on October 24, 2026.
The tool, called hex-MASP, maps the whole-tissue spatial proteome as well as the distribution within the brain of monoclonal antibodies. The research was published by Shihan Huo and colleagues in the Proceedings of the National Academy of Sciences in 2026.
Using hex-MASP, the lab has already identified promising new candidates for Alzheimer’s disease drug targets, with further research under way. The stated ambition is to help researchers discover better targets and develop treatments that make a greater difference for patients.
The tool could also help teams improve a drug candidate — or reconsider its target — before committing to costly clinical trials, potentially saving years of work.
Read also: US awards $389 million for power semiconductors and NASA holds Artemis acceleration briefing
Bhudev Bhagaliya is an experienced and senior journalist who has carved a distinct niche for himself in the world of Hindi journalism through his profound understanding and precise writing style. With over two decades of experience in the field of journalism, he has held key responsibilities at Dainik Hindustan for 12 years and at Amar Ujala for one year. Currently, he serves as the Content Editor for the Jagrook Youth News newspaper and portal, where he plays a crucial role in ensuring the quality and credibility of the news content. Bhudev Bhagaliya consistently writes about issues that help raise awareness within society and among the younger generation.